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Estrogen can be both a beneficial and a harmful hormone. It maintains skeletal strength by preventing the loss of bone and enhancing calcium retention. However, estrogen causes the proliferation of cells in the breast and the uterus, which can increase a woman's chance of developing cancer at these sites.
Selective estrogen-receptor modulators (SERMs), such as tamoxifen and raloxifene, produce estrogen action in those tissues (e.g., bone, ...
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